comparison between conventional mechanical fixation and use of autologous platelet rich plasma (prp) in wound beds prior to resurfacing with split thickness skin graft
نویسندگان
چکیده
background platelet rich plasma is known for its hemostatic, adhesive and healing properties in view of the multiple growth factors released from the platelets to the site of wound. the primary objective of this study was to use autologous platelet rich plasma (prp) in wound beds for anchorage of skin grafts instead of conventional methods like sutures, staplers or glue. methods in a single center based randomized controlled prospective study of nine months duration, 200 patients with wounds were divided into two equal groups. autologous prp was applied on wound beds in prp group and conventional methods like staples/sutures used to anchor the skin grafts in a control group. results instant graft adherence to wound bed was statistically significant in the prp group. time of first post-graft inspection was delayed, and hematoma, graft edema, discharge from graft site, frequency of dressings and duration of stay in plastic surgery unit were significantly less in the prp group. conclusion autologous prp ensured instant skin graft adherence to wound bed in comparison to conventional methods of anchorage. hence, we recommend the use of autologous prp routinely on wounds prior to resurfacing to ensure the benefits of early healing.
منابع مشابه
Comparison between Conventional Mechanical Fixation and Use of Autologous Platelet Rich Plasma (PRP) in Wound Beds Prior to Resurfacing with Split Thickness Skin Graft
BACKGROUND Platelet rich plasma is known for its hemostatic, adhesive and healing properties in view of the multiple growth factors released from the platelets to the site of wound. The primary objective of this study was to use autologous platelet rich plasma (PRP) in wound beds for anchorage of skin grafts instead of conventional methods like sutures, staplers or glue. METHODS In a single ...
متن کاملComparison between Conventional Mechanical Fixation and Use of Autologous Platelet Rich Plasma (PRP) in Wound Beds Prior to Resurfacing with Split Thickness Skin Graft
BACKGROUND Platelet rich plasma is known for its hemostatic, adhesive and healing properties in view of the multiple growth factors released from the platelets to the site of wound. The primary objective of this study was to use autologous platelet rich plasma (PRP) in wound beds for anchorage of skin grafts instead of conventional methods like sutures, staplers or glue. METHODS In a single c...
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Background: Healing involves complex processes that are not yet fully known. The wound healing process consists of three stages. In all these stages, normal wound healing requires platelet activation, release of cytokines and growth hormones, and chemotaxis and cell differentiation. Platelets play a key role in homeostasis and wound healing and growth factor production of more than 30 carried o...
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Effects of Platelet Rich Plasma (PRP) and Platelet Rich Growth Factor (PRGF®)on the Wound Healing of Distal Part of Limbs in Horses
Objectives- To evaluate the efficacy of platelet rich- plasma (PRP) and plasma rich-growth factor (PRGF®) on the wound healing on distal aspect of horses limbs. Design- Experimental study Animals - Four mixed- breed adult horses, 13 to 21 years of age and weighting 381 ±85 kg Procedures- The Limbs of each horse were treated with PRP, PRGF®, Silver Sulfa diazin and one limb received no treatment...
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عنوان ژورنال:
world journal of plastic surgeryجلد ۴، شماره ۱، صفحات ۵۰-۵۹
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